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Arbutin
- Name Arbutin
- CAS 497-76-7
- Purity 99%
Product Details
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1.What is the Arbutin ?
Arbutin has bactericidal, anti-inflammatory, and whitening effects and is mainly used in whitening cosmetics.
veterinary drug
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14698-56-7
4-acetoxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside
-
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497-76-7
arbutin
| Conditions | Yield |
|---|---|
|
With
ammonium chloride;
In
water;
at 70 ℃;
for 2h;
Concentration;
|
90%
|
|
With
di(n-butyl)tin oxide;
In
methanol;
for 8h;
Heating;
|
87.7%
|
|
4-acetoxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside;
With
sodium methylate;
In
methanol;
for 4h;
Heating / reflux;
28% NaOMe;
With
acetic acid;
In
methanol;
for 0.5h;
AcOH was added after cooling;
Stirring;
|
81%
|
|
4-acetoxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside;
With
sodium hydroxide;
In
methanol;
for 5h;
Heating / reflux;
With
acetic acid;
In
methanol;
for 0.5h;
AcOH was added after cooling;
Stirring;
|
80%
|
|
4-acetoxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside;
With
sodium hydroxide;
In
methanol;
for 7h;
Heating / reflux;
With
formic acid;
In
methanol;
for 0.5h;
HCOOH was added after cooling;
Stirring;
|
79%
|
|
4-acetoxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside;
With
potassium hydroxide;
In
methanol;
for 5h;
Heating / reflux;
With
acetic acid;
In
methanol;
for 0.5h;
AcOH was added after cooling;
Stirring;
|
77%
|
|
With
methanol; sodium methylate;
at 80 ℃;
for 5h;
|
-
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2872-65-3,14581-81-8,17042-40-9,84380-06-3,105260-62-6
p-methoxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside
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-
497-76-7
arbutin
| Conditions | Yield |
|---|---|
|
With
copper(I) oxide; sodium methylate;
In
methanol;
at 0 - 80 ℃;
for 4h;
|
95%
|
2.What is the CAS number for Arbutin ?
The CAS number of Arbutin is 497-76-7.
More information of Arbutin 497-76-7 are:
|
CAS?Number |
497-76-7 |
|
Density |
1.556 g/cm3 |
|
Melting Point |
195-198 °C |
|
Boiling Point |
561.583 °C at 760 mmHg |
|
Flash Point |
293.435 °C |
|
Vapor Pressure |
1.9E-13mmHg at 25°C |
|
Refractive Index |
-65.5 ° (C=4, H2O) |
|
HS CODE |
2938.90 CLASSIFICATION |
|
PSA |
119.61000 |
|
LogP |
-1.42910 |
|
Pka |
10.10±0.15(Predicted) |
3.What are another words for Arbutin ?
Synonyms?for?Arbutin 497-76-7:.beta.-D-Glucopyranoside, 4-hydroxyphenyl;(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol;Arbutoside;Hydroquinone beta-D-glucopyranoside;2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol;beta-D-Glucopyranoside, 4-hydroxyphenyl- (9CI);hexopyranoside, 4-hydroxyphenyl;(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol;beta-Arbutin;Ursin;Uvasol;4-hydroxyphenyl hexopyranoside;4-Hydroxyphenyl-beta-D-glucopyranoside;p-Hydroxyphenyl beta-D-glucopyranoside;(3R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol;4-Hydroxyphenyl beta-D-glucopyranoside;4-hydroxyphenyl β-D-glucopyranoside;β-Arbutin;4-Hydroxyphenyl-β-D-glucopyranoside;
4.What is the molecular formula of Arbutin?
The chemical formula of ?Arbutin is?C12H16O7 which containing 12 Carbon atoms,16 Hydrogen atoms and 7 Oxygen atoms,and the molecular weight of??Arbutin?is 272.255.
5.What is Arbutin (497-76-7) used for?
Arbutin is a glycosylated hydroquinone that has been found in Arctostaphylos plants and has diverse biological activities, including tyrosinase inhibitory, antioxidant, and anti-inflammatory properties. It inhibits human tyrosinase activity in crude tyrosinase solution isolated from human melanocytes (IC50s = 5.7 and 18.9 mM using L-tyrosine and L-DOPA as substrates, respectively) as well as in intact melanocytes (IC50 = 0.5 mM). Arbutin (50 μM) inhibits hemolysis induced by the free radical generator AAPH in sheep erythrocytes and inhibits AAPH-induced decreases in cell viability in cultured human skin fibroblasts when used at concentrations greater than 125 μM. In an LPS-induced rat model of acute lung injury, arbutin (50 mg/kg) prevents increases in IL-1β, IL-6, and TNF-α levels in lung tissue and serum. Formulations containing arbutin have been used in the treatment of hyperpigmentation disorders.
InChI:InChI=1/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9+,10+,11-,12-/m1/s1
Relevant articles related to Arbutin:
|
Article |
Source |
|
High-Field Formation of Arbutin from Hydroquinone by Cell-Suspension Cultures of Rauwolfia serpentina |
Lutterbach, Ralf,Stoeckigt, Joachim , p. 2009 - 2011 (1992) |
|
α-Glucosidic hydroquinone derivatives from Viburnum erosum |
Choi, Seong Yeon,Jang, Hyeon Seok,Jeong, Birang,Kim, Juyeol,Kwon, Yong Soo,Lee, Jiho,Park, Jinyoung,Yang, Heejung , (2021/05/03) |
6.Buy Arbutin with the best price .
Hebei Lvyang Biotechnology Co., Ltd. is a quality supplier of Arbutin. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Arbutin 497-76-7.
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